tert-Butyl 3-bromobenzyl(methyl)carbamate

tert-Butyl 3-bromobenzyl(methyl)carbamate - Names and Identifiers

Name	Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester
Synonyms	N-Boc-N-Methyl-3-broMobenzylaMine tert-Butyl 3-bromobenzyl(methyl)carbamate tert-butyl (3-bromo-benzyl)-N-methylcarbamate (3-BROMO-BENZYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER tert-Butyl N-[(3-bromophenyl)methyl]-N-methylcarbamate Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester Carbamic acid, N-[(3-bromophenyl)methyl]-N-methyl-, 1,1-dimethylethyl ester
CAS	317358-61-5

tert-Butyl 3-bromobenzyl(methyl)carbamate - Physico-chemical Properties

Molecular Formula	C13H18BrNO2
Molar Mass	300.19
Density	1.295±0.06 g/cm3(Predicted)
Boling Point	354.5±21.0 °C(Predicted)
pKa	-1.46±0.70(Predicted)
Storage Condition	2-8°C

tert-Butyl 3-bromobenzyl(methyl)carbamate - Introduction

Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester (Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester) is an organic compound. Its molecular formula is C12H15BrNO2 and its molecular weight is 294.16g/mol.

The following are some important Properties, Uses, preparation and safety information of the compound:

Nature:
-Appearance: Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester is in the form of white crystals or crystalline powder.
-Melting point: about 82-85°C.
-Boiling Point: Not applicable.

Use:
Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester can be used as intermediates in organic synthesis and used in the synthesis of other organic compounds. It is commonly used in the pharmaceutical field, for example as a starting material for the synthesis of drugs or as a pharmaceutical intermediate. In addition, it can also be used in the synthesis of pesticides, dyes and other chemicals.

Method:
A commonly used preparation method is to react benzoate with methylamine to obtain the corresponding methyl carbamate intermediate, and then react with 3-bromobenzyl bromide under alkali catalysis to form the final product.

Safety Information:
Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester is generally relatively safe under normal operating conditions, but the following matters still need to be paid attention:
-It may be irritating to the skin, eyes and respiratory system, so use protective measures such as gloves, goggles and breathing apparatus.
-Avoid inhaling the dust or vapor of the compound and operate in a well-ventilated place.
-Do not eat or drink, and keep away from food and beverages.
-Store it in a dry, cool place and away from fire and oxidizing agents.

when using Carbamic acid, [(3-bromophenyl)methyl]methyl-, 1,1-dimethylethyl ester, it is recommended to operate according to relevant safety operation regulations, and use under the guidance of experienced chemical professionals.

Last Update：2024-04-09 20:52:54